Publications

Found 6 results
2014
Janssen FJ, Deng H, Baggelaar MP, Allarà M, van der Wel T, Dulk Hden, Ligresti A, van Esbroeck ACM, McGuire R, Di Marzo V et al..  2014.  Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6. Journal of Medicinal Chemistry. 57(15) 6610-6622.
Ghisaidoobe AT, van den Berg RJBHN, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AMCH, Koomen G-J, van Loevezijn A, Leemhuis M et al..  2014.  Identification and Development of Biphenyl Substituted Iminosugars as Improved Dual Glucosylceramide Synthase/Neutral Glucosylceramidase Inhibitors. Journal of Medicinal Chemistry. 57(21) 9096-9104.
Willems MMJHP, Zom GG, Khan S, Meeuwenoord N, Melief CJM, van der Stelt M, Overkleeft HS, Codée JDC, van der Marel GA, Ossendorp F et al..  2014.  N-Tetradecylcarbamyl Lipopeptides as Novel Agonists for Toll-like Receptor 2. Journal of Medicinal Chemistry. 57(15) 6873-6878.
de Bruin G, Huber EM, Xin B-T, van Rooden EJ, Al-Ayed K, Kim K-B, Kisselev AF, Driessen C, van der Stelt M, van der Marel GA et al..  2014.  Structure-Based Design of β1i or β5i Specific Inhibitors of Human Immunoproteasomes. Journal of Medicinal Chemistry. 57(14) 6197-6209.
2013
Geurink PP, van der Linden WA, Mirabella AC, Gallastegui N, de Bruin G, Blom AEM, Voges MJ, Mock ED, Florea BI, van der Marel GA et al..  2013.  Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites. Journal of Medicinal Chemistry. 56(3) 1262-1275.
2011
van der Stelt M, Cals J, Broeders-Josten S, Cottney J, van der Doelen AA, Hermkens M, de Kimpe V, King A, Klomp J, Oosterom J et al..  2011.  Discovery and Optimization of 1-(4-(Pyridin-2-yl)benzyl)imidazolidine-2,4-dione Derivatives As a Novel Class of Selective Cannabinoid CB2 Receptor Agonists. Journal of Medicinal Chemistry. 54(20) 7350-7362.